|
Symbol Name ID |
Gja5
gap junction protein, alpha 5 MGI:95716 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Increased circulating troponin T concentration |
Abnormal heart morphology |
Left atrial enlargement |
Left ventricular hypertrophy |
Right ventricular dilatation |
Tetralogy of Fallot |
Endocardial fibroelastosis |
Left ventricular noncompaction |
Cardiomyopathy |
Atrial cardiomyopathy |
Stroke |
Ischemic stroke |
Reduced left ventricular ejection fraction |
Elevated left ventricular end-diastolic diameter |
Aortic valve stenosis |
Tricuspid regurgitation |
Hypertension |
Abnormal P wave |
Prolonged P wave |
Prolonged PR interval |
Prolonged QRS complex |
Prolonged QTc interval |
ST segment elevation |
Arrhythmia |
Sick sinus syndrome |
Sinus bradycardia |
Bradycardia |
Sudden cardiac death |
Palpitations |
Atrial fibrillation |
Paroxysmal atrial fibrillation |
Permanent atrial fibrillation |
Atrial flutter |
Atrial standstill |
Premature atrial contractions |
Supraventricular tachycardia |
Ventricular tachycardia |
Ventricular escape rhythm |
Cardiac conduction abnormality |
First degree atrioventricular block |
Mobitz I atrioventricular block |
Right bundle branch block |
Myocardial infarction |
Congestive heart failure |
Syncope |
| Disease(s) Associated with GJA5 | |||||||||||||||||||||||||||||||||||||||||||||
| atrial standstill 1 | |||||||||||||||||||||||||||||||||||||||||||||
| familial atrial fibrillation | |||||||||||||||||||||||||||||||||||||||||||||
| tetralogy of Fallot |
| Mouse Phenotypes | cardiovascular system phenotype |
abnormal blood vessel morphology |
pulmonary artery hypoplasia |
abnormal aortic arch and aortic arch branch attachment |
abnormal atrioventricular cushion morphology |
abnormal heart morphology |
double outlet right ventricle |
mitral valve stenosis |
common atrioventricular valve |
bifid atrial appendage |
ostium primum atrial septal defect |
ventricular septal defect |
dilated cardiomyopathy |
increased heart rate |
irregular heartbeat |
abnormal impulse conducting system conduction |
prolonged PR interval |
abnormal frontal plane axis |
prolonged P wave |
prolonged PQ interval |
abnormal QRS complex |
fragmented QRS complex |
prolonged QRS complex duration |
prolonged QT interval |
bundle branch block |
decreased mean systemic arterial blood pressure |
|
| Availability | Mouse Genotype | ||||||||||||||||||||||||||
| Gja5tm1Kwi/Gja5tm1Kwi | |||||||||||||||||||||||||||
| Gja5tm1Paul/Gja5tm1Paul | |||||||||||||||||||||||||||
| Gja5tm2.1Kwi/Gja5tm2.1Kwi | |||||||||||||||||||||||||||
| Gja5tm1Paul/Gja5+ | |||||||||||||||||||||||||||
| Tg(Tie2-Gja5*,-EGFP)#Dach/0 | * | ||||||||||||||||||||||||||
| Tg(Tie2-Gja5,-EGFP)#Dach/0 | * | ||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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